We've got a client who recently upgraded their Windows Server 2008 Remote Desktop Services box from Office 2003 to Office 2010. In doing so, they ran up against Internet File Blocking which Office 2010 seems to take seriously, where Office 2003 ignored it.
With Windows XP now pretty much impossible to get preloaded on new machines, our clients are finally moving to Windows 7 as their hardware refreshes.
A segment of our clients uses an application built upon Filemaker Pro, and they're running v9.03 which isn't the most Windows 7 friendly version of Filemaker (that honor is reserved for any of the versions released in the last 3 years). As we roll out Windows 7, we have found that databases hosted on remote servers don't show up in their Open Remote.