We've got a client who recently upgraded their Windows Server 2008 Remote Desktop Services box from Office 2003 to Office 2010. In doing so, they ran up against Internet File Blocking which Office 2010 seems to take seriously, where Office 2003 ignored it.
Chrome is a pretty fantastic browser; in fact, I'm using it right now! However, it wants to live in your AppData directory, and that's a drag for users on Terminal Servers since administrators can't easily install the application into that location, and users can't install it themselves if they're not administrators.
There are times when Microsoft makes me wonder. You develop this cool technology, ClearType, which helps reduce eyestrain, you put checkboxes all over the Remote desktop client allowing me to choose to use or not use it, you have it active in the shell.